MP4 is the default winner
For most people, MP4 is the safest destination format. It works on phones, browsers, social platforms, messaging apps, and most editing tools. If a MOV, MKV, AVI, WMV, FLV, or 3GP file will not open somewhere, converting it to MP4 is usually the first move.
WebM can be excellent for browser-first workflows, while MOV remains common for Apple and camera exports.
Container and codec matter
A file extension like MKV or MP4 is a container. The video and audio inside may use different codecs. A conversion can change the container, the codec, or both, which affects compatibility, size, and quality.
If a video uploads but will not play, the issue is often codec support rather than the extension alone. Converting to a common MP4 profile is a practical compatibility fix.
Before you upload
After conversion, check the first seconds, a fast-motion section, a quiet audio section, and the final timestamp. This catches sync problems, black frames, and cut-off endings before you publish or send the file.